Comprehensive Down Syndrome Program
Dedicated to providing comprehensive services and compassionate care for individuals with Down syndrome across the life span.
Appointments
The Duke Comprehensive Down Syndrome Program was developed to provide family-centered medical care for individuals with Down syndrome. Using the guidelines developed by the Down Syndrome Medical Interest Group for systematic, preventative care, our physicians work in conjunction with the patient's primary care provider. The clinic team focuses on maximizing the development of individuals with Down syndrome by managing medical issues, connecting them with community resources, and teaching families to advocate for their children. The clinic has provided specialty care to over 1,000 patients and their families since its inception in 1995.
Photo Credit: Melissa Cackovic
Treatments
The Duke Comprehensive Down Syndrome Program is a multidisciplinary referral clinic for the management of Down syndrome in infants, toddlers, children, and young adults. We also see expectant parents as part of our clinical services.
Our core clinical physicians and staff have expertise in Down syndrome. We provide same-day access to specialists in order to reduce the number of hospital/clinic visits for patients and their families. We can also arrange for your child need to see a specialist from our ancillary services, or any physician within the Duke Health System. A coordinated approach to care allows our team to observe medical, social, and behavioral concerns common to the Down syndrome population.
Clinical research is an important component of our program. The goal of the crossdisciplinary research that occurs in our facility is to accelerate healthcare and quality of life outcomes for individuals with Down syndrome.
Physicians
| Name | Role |
|---|---|
| Priya S. Kishnani, MD | Co-Director, Pediatric Geneticist |
| Gordon Worley, MD | Co-Director, Neurodevelopmental Pediatrician |
| Vandana Shashi, MD | Pediatric Geneticist |
| Terri L. Young, MD | Pediatric Ophthalmologist, Ophthalmic Genetics |
| Laura B. Enyedi, MD | Pediatric Ophthalmologist |
| James Burke, MD | Neurologist, Alzheimer's Disease |
| Eileen M. Raynor, MD | Pediatric Otolaryngologist |
| Angelo S. Milazzo, MD | Pediatric Cardiologist |
| Michael G.W. Camitta, MD | Pediatric Cardiologist |
| Stephanie Burns Wechsler, MD | Pediatric Cardiologist |
| Robert D. Fitch, MD | Pediatric Orthopedist |
| Neil S. Prose, MD | Pediatric Dermatologist |
| Nancy Friedman, MD | Pediatric Endocrinologist |
| Nancie MacIver, MD | Pediatric Endocrinologist |
| Richard M. Kravitz, MD | Pediatric Pulmonologist |
| John S. Wiener, MD | Pediatric Urologist |
Core Clinical Staff
Ancillary Services
| Name | Role |
|---|---|
| David K. Wallace, MD, MPH | Pediatric Ophthalmologist |
| Sharon F. Freedman, MD | Pediatric Ophthalmologist |
| Jennifer S. Li, MD | Pediatric Cardiologist |
| Michael P. Carboni, MD | Pediatric Cardiologist |
| Michael S. Freemark, MD | Pediatric Endocrinologist |
| Robert W. Benjamin, MD | Pediatric Endocrinologist |
| Deanna W. Adkins, MD | Pediatric Endocrinologist |
| Martin H. Ulshen, MD | Pediatric Gastroenterologist |
| Philip M. Rosoff, MD | Pediatric Hematologist-Oncologist |
| Courtney D. Thornburg, MD, MS | Pediatric Hematologist-Oncologist |
| Corinne M. Linardic, MD, PhD | Pediatric Hematologist-Oncologist |
| Susan G. Kreissman, MD | Pediatric Hematologist-Oncologist |
| Daniel S. Wechsler, MD, PhD | Pediatric Hematologist-Oncologist |
| Andrew J. Lodge, MD | Pediatric Cardiothoracic Surgeon |
| Martha Ann Keels, PhD, DDS | Pediatric Dentist |
| William B. Gallentine, DO | Pediatric Neurologist |
| Henry E. Rice, MD | Pediatric Surgeon |
| Gail A. Spiridigliozzi, PhD | Pediatric Psychologist |
Research Collaborators
| Name | Role |
|---|---|
| Harrison Jones, PhD | Speech Pathologist |
| Gail A. Spiridigliozzi, PhD |
Pediatric Psychologist |
| James Heller, MA, MS | Speech Language Pathologist |
| Donald C. Lo, PhD | Center for Drug Discovery |
| David Millington, PhD | Director, Biochemical Genetics Laboratory |
| P. Murali Doraiswamy, MD | Psychiatry & Behavioral Sciences |
| K. Ranga Krishnan, MB, ChB | Psychiatry & Behavioral Sciences |
| Alex Kemper, MD, MPH, MS | Primary Care Pediatrics |
Clinic Hours & Locations
Lenox Baker Children's HospitalDurham, NC 27705
Tel: 919-684-6669
Hours: First and third Thursdays of each month, 8:00 am - 3:00 pm
Additional Locations
For patient convenience, ours services are also provided at the following additional locations:
2301 Erwin Road
Durham, NC 27710
Tel: 919-668-4000
Hours: Daily, 8:30 am - 5:00 pm
3427 Melrose Road
Fayetteville, NC 28304
Tel: 910-323-5940
3480 Wake Forest Road, Suite 310
Raleigh, NC 27609
Appointments: 919-668-4000
Office: 919-862-5750
Greensboro, NC 27401
Hours: Monday to Friday, 8:00 am - 4:30 pm
Durham, NC 27704
Appointments and Contact Information
- For appointments for new patients, please complete the appropriate form (Adult [PDF, 82.83KB] or Pediatric [PDF, 28.5KB]) and send information to Blythe G. Crissman via phone or fax.
- Phone: 919-681-1976
- Fax: 919-668-0414
- For appointments for returning patients, please call Sandra Durden at 919-684-0307.
- For billing and insurance questions, please call Kristie Lyons at 919-684-4217.
Quick Links
- Medical Genetics Home
(Duke Children's) - Division of Medical Genetics
(Duke School of Medicine)
- Clinical Genetics Services
- Pompe Disease Clinical and Research Program
- Comprehensive Down Syndrome Program
- Glycogen Storage Disease Clinical and Research Program
- General Genetics Clinic
- Metabolic Clinic
- Autism/Medical Genetics Clinic
- Cardiovascular Genetics Clinic
- Fragile X Syndrome Clinic
- Marfan/Connective Tissue Disorder Genetics Clinic
- 22q11 Deletion Syndrome Clinic
Related Links
- Triangle Down Syndrome Network
- National Down Syndrome Society
- National Down Syndrome Congress
- Anna's Angels
Healthcare Links
Research Links
- Clinical Trials Research for Down Syndrome
- Publications [PDF, 21.8KB]
Clinic Forms
- New Patient Referral Form (Adult) [PDF, 82.83KB]
- New Patient Referral Form (Pediatric) [PDF, 28.5KB]
Upcoming Events
- 9th Annual Anna's Angels Gala
- When: Saturday, March 10, 2012
- Time: 6:00pm - midnight
- Where: Prestonwood Country Club, Cary, NC [Directions]
- Tickets: Tickets may be purchased online or by mail.
- Details: Visit the event page for additional information.
How Are Anna's Angels Funds Used?
The funds raised by Anna's Angels have been significant in developing a viable Down syndrome research infrastructure at Duke. The biobank and registry have been key to the success of our research program. We are funding promising speech therapy, cognitive remediation, and Duke is one of the lead universities in a Roche pharmaceuticals study focusing on cognition and memory.
There are many ways you can help in the fight against Down syndrome. Concerned individuals, companies and organizations have made it possible for Duke University to continue its research efforts and programs to aid those with Down syndrome and their families. If you would like to make a contribution, please visit our online form and specify Down Syndrome Research in the Gift Designation section.
