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Site-Based Research

Overview of Site-Based Research at Duke

Each year, more than 1,000 faculty and study coordinators at Duke enroll patients in clinical trials that involve medical treatment. Recently, a site-based research organization was created to ensure that these trials are ethically and efficiently managed, which will ultimately improve the overall quality of the patient care experience and provide the highest quality clinical research environment possible.

Under the new site-based research organization, each academic department or therapeutic area has established--in conjunction with the Clinical Research Support Office (CRSO)--a site-based research (SBR) group or unit to oversee all clinical research that involves medical care in that area. The Department of Pediatrics has its own group, the Pediatric Site-based Research Unit (SBRU).

Each SBR has certain key components including:
  • Faculty members in a particular therapeutic area who are enrolling Duke patients in clinical research studies that involve medical care
  • Study coordinators and research staff who are specifically aligned with this faculty group
  • A faculty advisory board
  • A director (usually a faculty member)
  • A lead study coordinator
  • A financial manager
However, because of the diverse nature of research at Duke, departments have defined individual operating models that work most effectively in their respective areas.
To ensure consistency and clarity of responsibilities and procedures within the Department of Pediatrics and Duke Children's Hospital & Health Center, a Manual of Operations for all pediatric clinical research investigators has been developed and is available here to download.

Find a Clinical Trial

Duke University Medical Center has established a clinical trials network to ensure that patients have access to cutting edge medicines and therapies. Clinical trials take place under the most stringent guidelines, and participants benefit from closely supervised care.

To find current clinical trials, browse the list or select a category from the drop-down menu on dukehealth.org.